Gene name:
ZC3H8 (ZC3HDC8) ;
Protein name:
Zinc finger CCCH domain-containing protein 8 ;
Alternative:
Organism:
Human (Homo sapiens).
General Annotation
Function:
Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MDFENLFSKP | PNPALGKTAT | DSDERIDDEI | DTEVEETQEE | KIKLECEQIP |
100:
KKFRHSAISP | KSSLHRKSRS | KDYDVYSDND | ICSQESEDNF | AKELQQYIQA |
150:
REMANAAQPE | ESTKKEGVKD | TPQAAKQKNK | NLKAGHKNGK | QKKMKRKWPG |
200:
PGNKGSNALL | RNSGSQEEDG | KPKEKQQHLS | QAFINQHTVE | RKGKQICKYF |
250:
LERKCIKGDQ | CKFDHDAEIE | KKKEMCKFYV | QGYCTRGENC | LYLHNEYPCK |
291:
FYHTGTKCYQ | GEYCKFSHAP | LTPETQELLA | KVLDTEKKSC | K
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human Zinc finger CCCH domain-containing protein 8
ELISA Kit for Human Zinc finger CCCH domain-containing protein 8
CLIA Kit for Human Zinc finger CCCH domain-containing protein 8
CLIA Kit for Human Zinc finger CCCH domain-containing protein 8
Polyclonal Antibody for Human Zinc finger CCCH domain-containing protein 8
Polyclonal Antibody for Human Zinc finger CCCH domain-containing protein 8
Monoclonal Antibody for Human Zinc finger CCCH domain-containing protein 8
Monoclonal Antibody for Human Zinc finger CCCH domain-containing protein 8
Protein for Human Zinc finger CCCH domain-containing protein 8
Protein for Human Zinc finger CCCH domain-containing protein 8
R&D Technical Data
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Skin .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
5.
"ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."
Matsuoka S.
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Ballif B.A.
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Smogorzewska A.
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McDonald E.R. III
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Hurov K.E.
,
Luo J.
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Bakalarski C.E.
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Zhao Z.
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Solimini N.
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Lerenthal Y.
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Shiloh Y.
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Gygi S.P.
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Elledge S.J.
Science316:1160-1166(2007)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-77;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Embryonic kidney .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-77;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-32;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Leukemic T-cell .
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
10.
"The little elongation complex functions at initiation and elongation phases of snRNA gene transcription."
Hu D.
,
Smith E.R.
,
Garruss A.S.
,
Mohaghegh N.
,
Varberg J.M.
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Lin C.
,
Jackson J.
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Gao X.
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Saraf A.
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Florens L.
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Washburn M.P.
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Eissenberg J.C.
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Shilatifard A.
Mol. Cell51:493-505(2013)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SUBCELLULAR LOCATION;IDENTIFICATION IN THE LEC COMPLEX;INTERACTION WITH ICE1